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Pharmaceuticals Stocks

Galapagos Faces Uncertain Future Amidst CAR-T Therapy Pivot

Galapagos (GLPG) $27 pivots to CAR-T therapy, divesting Jyseleca; faces clinical, market risks amidst investor skepticism. Divestiture of its Jyseleca business reflects a significant shift in its business strategy. There are dissenting opinions on whether this was a good move.

Revenue up 9% YOY; operating losses reduced; strong cash reserve at $4.2B; 

  • Negative enterprise value and underperforming stock; high short interest and bearish investor sentiment.
  • A lot of uncertainties in CAR-T strategy, competitive landscape, and market skepticism. The CAR-T therapy landscape is intensely competitive, and the success of Galapagos’ key candidates, GLPG5101 and GLPG5201, is imperative.
    • Pipeline and R&D Success Rate: Concentrating on CAR-T therapies, particularly GLPG5101 and GLPG5201, presents significant risks. Nevertheless, the EUPLAGIA-1 study’s preliminary data reveals encouraging results. In the study, 75% of CLL patients (12 out of 16) who received GLPG5101 achieved Complete Response with no report of serious adverse effects. In contrast, the GLPG5201 treatment group faced more severe outcomes, with 2 out of 14 patients encountering fatal (Grade 5) events, and a few others experiencing life-threatening or disabling (Grade 4) complications.

This is from a biotech analyst, he’s bearish but a couple of other biotech specialists were bullish in 2023, but haven’t published any updates.

Wall Street has a hold rating.

Categories
Cloud Service Providers Stocks

 A Cloud Storage Titan Struggling to Stay Relevant

Dropbox (DBX) $21.25 – I’m Neutral On This Company

Dropbox has been quite the underperformer, in the last 5 years the stock has lost 7%, and 8% in the past year.

Sales growth has really slowed down from 8-10% to only 3-4% expected for the next 3 years and that’s why there’s no appreciation for the stock. Its a fairly profitable company 15-16% operating margins and cash flow of 30+% because of the high stock-based compensation. Earnings growth is also tepid with just 6-8% expected for the next three years. These are two big reasons why there isn’t much scope for Dropbox to grow.

Dropbox is proving to be less sticky than originally thought. As churn rates have increased over the past year, many investors are re-evaluating the stickiness and value of Dropbox’s subscription revenue base.

Deep competition- Dropbox has always been in an eternal tug-of-war with competitors Google Drive (which has an advantage in pricing and integration with consumer email accounts) and Box, Inc. (BOX), which is better known for its enterprise-grade features and security.

Confidence in Dropbox faltered even more after the company reported rather dismal Q1 results – Analysts have an average hold rating.

Box (BOX), which is about 40% the size of Dropbox, not surprisingly, has a better growth profile with 6-7% revenue growth and 11-12% earnings growth expected in the next 3-4 years. It has a similar valuation multiple, so it’s not like that the markets have given it too much of a premium. 

The main thing is that growth will likely be in the low to mid-single digits in this industry, so can’t expect too much in terms of return from either. 

The one thing Dropbox/Box could do is to put their cash to better use (both generate in excess of 30% cash margins) and buyback shares, the valuations are low enough, which would help them and also help investors. For now, its neutral – don’t see much scope for expansion.

Categories
Cybersecurity

Fortinet (FTNT) at $74: HOLD as Price Target Met, 10% Post-Earnings Pop Overdone

source

The long term story remains intact – it is currently fully priced to add more.

Fortinet released Q4-23, earnings after market yesterday.

While the results and guidance were good and met expectations, the 10% pop from $67 yesterday is overdone. In the previous quarter, Fortinet under performed and the stock was pummeled 25% – last evening’s reaction was more of a sigh of relief that results met expectations. As you can see below, there’s nothing extraordinary.

  • Q4-23
  • Revenue of $1.42B (+10.9% Y/Y) beats by $10M.
  • Billings1: Total billings were $1.86 billion for the fourth quarter of 2023, an increase of 8.5% compared to $1.72 billion for the same quarter of 2022.
  • For Q1-2024  Everything is in line with expectations and forecasted analysts estimates.
  • Revenue $1.300 billion to $1.360 billion vs $1.38B consensus – In line.
  • Billings in the range of $1.390 billion to $1.450 billion
  • Non-GAAP gross margin in the range of 76.5% to 77.5% – In line
  • Non-GAAP operating margin in the range of 25.5% to 26.5% – In line
  • For 2024, Fortinet : These are also in line with previous guidance and forecasts.
  • Revenue $5.715 billion to $5.815 billion vs $5.94B consensus – Just over 10% growth.
  • Service revenue in the range of $3.920 billion to $3.970 billion
  • Billings in the range of $6.400 billion to $6.600 billion
  • Non-GAAP gross margin in the range of 76.0% to 78.0%
  • Non-GAAP operating margin in the range of 25.5% to 27.5%
  • Service Revenue growth was impressive and the highlight of the quarter. Service revenue was $927.0 million for the fourth quarter of 2023, an increase of 24.8% compared to $742.9 million YoY.